Overview
Long Name
|
Antibody Type
|
Antibody Isotype
|
Host
|
Species Reactivity
|
Validated Applications
|
Purification
|
| abl-interactor 2 |
Polyclonal |
IgG |
Rabbit |
Human, Mouse, Rat |
WB |
Immunogen affinity purified. |
Immunogen
|
| A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2(158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences. |
Properties
Form
|
Lyophilized |
Size
|
100 µg/vial |
Contents
|
Antibody is lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg NaN3. *carrier free antibody available upon request. |
Concentration
|
Reconstitute with 0.2 ml sterile dH2O (500 µg/ml final concentration). |
Storage
|
At -20 °C for 12 months, as supplied. Store reconstituted antibody at 2-8 °C for one month. For long-term storage, aliquot and store at -20 °C. Avoid repeated freezing and thawing. |
Additional Information Regarding the Antigen
Gene
|
ABI2 |
Protein
|
Abl interactor 2 |
Uniprot ID
|
Q9NYB9 |
Function
|
May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. |
Tissue Specificity
|
|
Sub-cellular localization
|
Cytoplasm . |
Sequence Similarities
|
Belongs to the ABI family. |
Aliases
|
Abelson interactor 2 antibody|ABI 2 antibody|ABI2B antibody|Abl binding protein 3 antibody|Abl interacting protein 1(SH3 containing protein) antibody|Abl interactor 2 antibody|Abl interactor protein 2b antibody|AblBP3 antibody|AIP 1 antibody|Arg binding protein 1 antibody|Arg protein tyrosine kinase binding protein antibody|ArgBP1 antibody|ARGBPIA antibody|ArgBPIB antibody|OTTHUMP00000163783 antibody|OTTHUMP00000163784 antibody|OTTHUMP00000206182 antibody|OTTHUMP00000206183 antibody|OTTHUMP00000206184 antibody|OTTHUMP00000206185 antibody|SSH3BP2 antibody |
Application Details
| Application |
Concentration* |
Species |
Validated Using** |
| Western blot |
0.1-0.5μg/ml |
Human, Rat Mouse |
AssaySolution's ECL kit |
AssaySolution recommends Rabbit Chemiluminescent WB Detection Kit (AKIT001B) for Western blot. *Blocking peptide can be purchased at $65. Contact us for more information
Anti-ABI2 antibody, ASA-B0024, Western blotting
Lane 1: Rat Brain Tissue Lysate
Lane 2: Human Placenta Tissue Lysate
Lane 3: MCF-7 Cell Lysate
Lane 4: HELA Cell Lysate
Lane 5: JURKAT Cell Lysate
